mir sensor assay Search Results


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Addgene inc 85865 plasmid 238378 238408
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Promega renilla luciferase sensors for d. melanogaster mir-2498, d. melanogaster mir-303, d. erecta mir-2498, and d. sechellia mir-303
Proof of principle for adaptive regulatory activity of newly evolved, testis-restricted miRNAs. Luciferase sensor assay tests for binding and regulatory potential of two seed-divergent, testes-specific, recently evolved miRNAs: ( A ) mir-2498 and ( B ) <t>mir-303</t> . ( Top ) miR homologs with three seed mismatches were assayed for regulatory potential to congruent sensor targets. ( Bottom ) In all cases, miRs significantly repressed their cognate targets but not noncognate ones. This test validates that divergent miRs of the same family (1) have regulatory potential for gene regulation and (2) base-identity constraint to repress only a set of specific-specific target genes.
Renilla Luciferase Sensors For D. Melanogaster Mir 2498, D. Melanogaster Mir 303, D. Erecta Mir 2498, And D. Sechellia Mir 303, supplied by Promega, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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BestGene Inc ubi- mir- 34- sensor plasmid
Proof of principle for adaptive regulatory activity of newly evolved, testis-restricted miRNAs. Luciferase sensor assay tests for binding and regulatory potential of two seed-divergent, testes-specific, recently evolved miRNAs: ( A ) mir-2498 and ( B ) <t>mir-303</t> . ( Top ) miR homologs with three seed mismatches were assayed for regulatory potential to congruent sensor targets. ( Bottom ) In all cases, miRs significantly repressed their cognate targets but not noncognate ones. This test validates that divergent miRs of the same family (1) have regulatory potential for gene regulation and (2) base-identity constraint to repress only a set of specific-specific target genes.
Ubi Mir 34 Sensor Plasmid, supplied by BestGene Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Isis Pharmaceuticals mir-143 overexpression and sensor plasmids
Proof of principle for adaptive regulatory activity of newly evolved, testis-restricted miRNAs. Luciferase sensor assay tests for binding and regulatory potential of two seed-divergent, testes-specific, recently evolved miRNAs: ( A ) mir-2498 and ( B ) <t>mir-303</t> . ( Top ) miR homologs with three seed mismatches were assayed for regulatory potential to congruent sensor targets. ( Bottom ) In all cases, miRs significantly repressed their cognate targets but not noncognate ones. This test validates that divergent miRs of the same family (1) have regulatory potential for gene regulation and (2) base-identity constraint to repress only a set of specific-specific target genes.
Mir 143 Overexpression And Sensor Plasmids, supplied by Isis Pharmaceuticals, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Optris GmbH mid-infrared temperature sensor csmicro 2w mid-infrared (mir)
Proof of principle for adaptive regulatory activity of newly evolved, testis-restricted miRNAs. Luciferase sensor assay tests for binding and regulatory potential of two seed-divergent, testes-specific, recently evolved miRNAs: ( A ) mir-2498 and ( B ) <t>mir-303</t> . ( Top ) miR homologs with three seed mismatches were assayed for regulatory potential to congruent sensor targets. ( Bottom ) In all cases, miRs significantly repressed their cognate targets but not noncognate ones. This test validates that divergent miRs of the same family (1) have regulatory potential for gene regulation and (2) base-identity constraint to repress only a set of specific-specific target genes.
Mid Infrared Temperature Sensor Csmicro 2w Mid Infrared (Mir), supplied by Optris GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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STEMCELL Technologies Inc mir-24-3p sensor
Proof of principle for adaptive regulatory activity of newly evolved, testis-restricted miRNAs. Luciferase sensor assay tests for binding and regulatory potential of two seed-divergent, testes-specific, recently evolved miRNAs: ( A ) mir-2498 and ( B ) <t>mir-303</t> . ( Top ) miR homologs with three seed mismatches were assayed for regulatory potential to congruent sensor targets. ( Bottom ) In all cases, miRs significantly repressed their cognate targets but not noncognate ones. This test validates that divergent miRs of the same family (1) have regulatory potential for gene regulation and (2) base-identity constraint to repress only a set of specific-specific target genes.
Mir 24 3p Sensor, supplied by STEMCELL Technologies Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


Proof of principle for adaptive regulatory activity of newly evolved, testis-restricted miRNAs. Luciferase sensor assay tests for binding and regulatory potential of two seed-divergent, testes-specific, recently evolved miRNAs: ( A ) mir-2498 and ( B ) mir-303 . ( Top ) miR homologs with three seed mismatches were assayed for regulatory potential to congruent sensor targets. ( Bottom ) In all cases, miRs significantly repressed their cognate targets but not noncognate ones. This test validates that divergent miRs of the same family (1) have regulatory potential for gene regulation and (2) base-identity constraint to repress only a set of specific-specific target genes.

Journal: RNA

Article Title: Adaptive evolution of testis-specific, recently evolved, clustered miRNAs in Drosophila

doi: 10.1261/rna.044644.114

Figure Lengend Snippet: Proof of principle for adaptive regulatory activity of newly evolved, testis-restricted miRNAs. Luciferase sensor assay tests for binding and regulatory potential of two seed-divergent, testes-specific, recently evolved miRNAs: ( A ) mir-2498 and ( B ) mir-303 . ( Top ) miR homologs with three seed mismatches were assayed for regulatory potential to congruent sensor targets. ( Bottom ) In all cases, miRs significantly repressed their cognate targets but not noncognate ones. This test validates that divergent miRs of the same family (1) have regulatory potential for gene regulation and (2) base-identity constraint to repress only a set of specific-specific target genes.

Article Snippet: Renilla luciferase sensors for D. melanogaster miR-2498, D. melanogaster miR-303, D. erecta miR-2498, and D. sechellia miR-303 were created using a modified version of psiCheck2 (Promega).

Techniques: Activity Assay, Luciferase, Binding Assay